HRID1099412

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16427141

5-Bromo-2-ethoxypyrimidine

C6H7BrN2O

结构：CC1(C)OB(c2cccc3c2C[C@H](N(Cc2ccccc2)Cc2ccccc2)CO3)OC1(C)C

HCID25114260

未命名化合物

PRODUCTS

生成物

结构：CCOc1ncc(-c2cccc3c2C[C@H](N(Cc2ccccc2)Cc2ccccc2)CO3)cn1

HCID25115370

未命名化合物

收率 62%

PROCEDURE

实验过程

The title compound was synthesized as described for Intermediate example I-28 in 62% yield starting from (3S)-N,N-dibenzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan -2-yl)chroman-3-amine and 5-bromo-2-ethoxypyrimidine. The reaction mixture was irradiated in a microwave at 140° C. for 20 min; MS (ESI) m/z 452[M+H+].

WORKUP

后处理

customThe reaction mixture was irradiated in a microwave at 140° C. for 20 min