Isopropanol → HCID 25116527, compound

HRID 1099431Notes

Reaction equation

HRID 1099431 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([C:8]([O:10]C)=[O:9])=[CH:4][N:3]=1.[CH:12]([OH:15])([CH3:14])[CH3:13]>>[CH:12]([O:15][C:2]1[N:3]=[CH:4][C:5]([C:8]([OH:10])=[O:9])=[CH:6][N:7]=1)([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 3776IsopropanolHCID 12627752Methyl 2-chloropyrimidine-5-carboxylate

Product 1

HCID 25116527HCID 25116527, compoundYield 14%

Procedure

The title compound was synthesized as described for Intermediate example I-81 in 14% yield starting from methyl 2-chloropyrimidine-5-carboxylate and isopropanol.

Sources & evidence

ORD record
ord-f51996aaaaa048678c6e7cbe030571dc
Source dataset
uspto-grants-2012_03
Patent number
US08143408B2

Reaction notes

Loading…