HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-salicylaldehyde → 3-(4-chloro-3-nitrobenzylsulfonyl)-6-chloro-2H-chromen-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-salicylaldehyde | HCID 12481 | — |
| Reactant | 2-(4-Chloro-3-nitrobenzylsulfonyl)acetic acid | HCID 66811160 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(4-chloro-3-nitrobenzylsulfonyl)-6-chloro-2H-chromen-2-one | HCID 11668786 | 93% |
Reaction Steps
A solution of 5-chlorosalicylaldehyde (1 mmol) and 2-(4-chloro-3-nitrobenzylsulfonyl)acetic acid (1 mmol) in acetic acid (10 mL) was subjected to the General Procedure 2, Method A to generate a 93% yield of the title compound; m.p. 272-275° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143428B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-84b8ffd190aa47c8a63cbf408924c5b5 |
| Source note | uspto-grants-2012_03 |