反应详情

温度

80 °C

A 300-ml two-necked flask equipped with a stirrer and a dropping funnel was charged with 25.1 g (0.33 mol) of 3-amino-1-propanol and 6.00 g of ethanol, and the contents were heated and stirred at 80° C. in a nitrogen atmosphere. After 9.00 g (33 mmol) of tetradecyl glycidyl ether were added dropwise over 2 hours, the resultant mixture was stirred further for 1 hour. The reaction mixture was poured into 400 ml of ice water and stirred for 1 hour. Crystals formed were then collected by filtration and recrystallized from methanol, thereby obtaining 15.4 g (yield: 92%) of the title compound (IIa-5).

1. customA 300-ml two-necked flask equipped with a stirrer and a dropping funnel
2. temperaturethe contents were heated
3. stirringstirred for 1 hour
4. customCrystals formed
5. filtrationwere then collected by filtration
6. customrecrystallized from methanol