Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1105491Generated: October 25, 2026

→ 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine

https://huagongshe.com/reaction/1105491

Reaction equation

Participants

RoleNameHCIDCharge
ReagentAcetaldehydeHCID 177—
ReagentSucroseHCID 5988—
ReagentTriethanolamineHCID 7618—
ReagentPotassium HydroxideHCID 14797—
ReagentManganese Chloride TetrahydrateHCID 643989—
ReagentHCID 178509096HCID 178509096—
SolventWaterHCID 962—
SolventIsopropanolHCID 3776—
Product2'-Deoxy-4'-C-ethynyl-2-fluoroadenosineHCID 648343176%

Reaction Conditions

Temperature35 °C
pH7.5

Provenance & Evidence

DOI10.1126/science.aay8484
Source datasetsynthesis of islatravir by biocatalytic cascade
ORD IDord-80ea7d29d01a42beae0627f615b2f314
Source notesynthesis of islatravir by biocatalytic cascade