→ 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine

HRID 1105491Notes

Reaction equation

Reactants or products are incomplete; the equation cannot be generated

Participants

9

Reactant 0

No Reactant data yet.

Product 1

HCID 64834312'-Deoxy-4'-C-ethynyl-2-fluoroadenosineYield 76%

Reagents, catalysts & solvents 8

HCID 177AcetaldehydeReagentHCID 5988SucroseReagentHCID 7618TriethanolamineReagentHCID 14797Potassium HydroxideReagentHCID 643989Manganese Chloride TetrahydrateReagentHCID 178509096HCID 178509096, compoundReagentHCID 962WaterSolvent3×HCID 3776IsopropanolSolvent

Conditions

Temperature
35 °C
pH
7.5

Workup

  1. filtrationThe filtrate contains the product and is kept. The solid residue is kept for washing. · Keep solid
  2. washNo procedure recorded
  3. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-80ea7d29d01a42beae0627f615b2f314
Source dataset
synthesis of islatravir by biocatalytic cascade
Original link
View source

Reaction notes

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