Hydrochloric Acid → 2-p-Ethoxyphenyl acrylic acid

HRID 1105506Notes

Reaction equation

HRID 1105506 reaction equation
C([O:3][C:4](=[O:17])[CH:5]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][CH3:16])=[CH:10][CH:9]=1)[CH2:6]O)C.Cl>[OH-].[K+]>[CH2:15]([O:14][C:11]1[CH:12]=[CH:13][C:8]([C:5](=[CH2:6])[C:4]([OH:17])=[O:3])=[CH:9][CH:10]=1)[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54407388Ethyl-2-p-ethoxyphenyl-3-hydroxypropionate

Product 1

HCID 705539292-p-Ethoxyphenyl acrylic acid

Reagents, catalysts & solvents 1

HCID 14797Potassium HydroxideSolvent

Procedure

The ethyl-2-p-ethoxyphenyl-3-hydroxypropionate (0.7 g) was refluxed for 7 h in potassium hydroxide solution (20%, 2 ml). It was acidified with dilute HCl and the crude acid (0.46 g, m.p. 103°-107°) used for the next step without further purification.

Workup

  1. customthe crude acid (0.46 g, m.p. 103°-107°) used for the next step without further purification

Sources & evidence

ORD record
ord-e97a6da48f7749f1a46ed8a5ec1265c5
Source dataset
uspto-grants-1982_01
Patent number
US04309350

Reaction notes

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