反应详情

A mixture of trans 3-bromocinnamic acid (m.p. 177°-179° C; 11.4 g), thienyl chloride (11.9 g) and dry benzene (150 ml) was heated at reflux for 2 hours. Solvent and excess thienyl chloride were removed by distillation under reduced pressure leaving trans 3-bromocinnamoyl chloride (12.2 g), b.p. 100°-100.5°C/0.2 mm Hg.

1. temperaturewas heated
2. temperatureat reflux for 2 hours
3. customSolvent and excess thienyl chloride were removed by distillation under reduced pressure