HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorothiophene → trans 3-Bromocinnamoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorothiophene | HCID 7299 | — |
| Reactant | m-Bromocinnamic acid | HCID 776461 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | trans 3-Bromocinnamoyl chloride | HCID 14959106 | 99% |
Reaction Steps
A mixture of trans 3-bromocinnamic acid (m.p. 177°-179° C; 11.4 g), thienyl chloride (11.9 g) and dry benzene (150 ml) was heated at reflux for 2 hours. Solvent and excess thienyl chloride were removed by distillation under reduced pressure leaving trans 3-bromocinnamoyl chloride (12.2 g), b.p. 100°-100.5°C/0.2 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04309444 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-65e19e89e86746dfbf9dab08e8910bab |
| Source note | uspto-grants-1982_01 |