HCID 15564129, compound → HCID 15564114, compound

Participants

Reaction Steps

1.42 G. of the thus-obtained crude 2-n-pentyl-3-ethoxyacrolein are dissolved in a sodium ethylate solution (obtained from 580 mg. of sodium in 40 ml. of ethanol) and treated with 2.6 g. of the aforementioned 4'-bromo-4-biphenylamidine hydrochloride. The mixture is stirred at room temperature for 3 days. After some of the solvent has been distilled off, water is added and the mixture is extracted with chloroform in the usual manner. Upon crystallization from ethanol, there is obtained 5-n-pentyl-2-(4'-bromo-4-biphenylyl)-pyrimidine in the form of needles, having a melting point of 137° C. and a clearing point of 197° C.

Provenance & Evidence