Chloroacetone → HCID 20524745, compound

Participants

Reaction Steps

A mixture of 4'-chloro-methanesulphonanilide (10.0 g), anhydrous potassium carbonate (4.0 g), chloroacetone (4.8 ml), and 1,2-dimethoxyethane was stirred and boiled under reflux for 24 hours, and then filtered, and the filtrate was evaporated. The oil residue was dissolved in ether, and the solution was washed with water, dried (MgSO4) and evaporated. The residue gave almost colourless crystals from acetone/40°-60° petrol. Melting point 108°. Yield 4.1 g.

Provenance & Evidence