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HRID1105758

反应详情

EQUATION

反应方程式

HRID 1105758 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：O=[N+]([O-])c1ccccc1S(=O)(=O)NOCc1ccccc1
HCID9839578

N-(Benzyloxy)-2-nitrobenzenesulfonamide

C13H12N2O5S

PRODUCTS

生成物

1
结构：CN(OCc1ccccc1)S(=O)(=O)c1ccccc1[N+](=O)[O-]
HCID20478825

未命名化合物

收率 76.9%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A mixture of 110.6 g of the product of Example 32, 49.8 g of anhydrous potassium carbonate, 55.8 g of methyliodide and 500 ml of acetone was stirred at ambient temperature for 20 hours. The solvent was evaporated and the residue partitioned between methylene chloride and water. Concentration of the organic extract afforded 88.9 g of N-methyl-N-(phenylmethoxy)-2-nitrobenzenesulfonamide as a yellow oil. [NMR:δ 2.8(s, 3H, NCH3)].

WORKUP

后处理

  1. customThe solvent was evaporated
  2. customthe residue partitioned between methylene chloride and water
  3. extractionConcentration of the organic extract