HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20555063, compound → HCID 20555100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20555063 | HCID 20555063 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20555100 | HCID 20555100 | — |
Reaction Steps
12 g of crude 6-(3-tert.-butylamino-2-hydroxypropoxy)-anthranilamide are dissolved in 400 ml of tetrahydrofurane and reduced, analogously to Example 4(e), with 6.1 g of lithium aluminium hydride for 48 hours. After working up, 2-aminomethyl-3-(3-tert.-butylamino-2-hydroxy-propoxy)-aniline is obtained in the form of an oil which is further used as such. It forms a tri-hydrochloride with a melting point of 250°-260° (with sublimation).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04310527 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-ee8ef6e0cfae467eb4f0e32fc021836f |
| Source note | uspto-grants-1982_01 |