Sodium Iodide → HCID 12852738, compound

HRID 1105882Notes

Reaction equation

HRID 1105882 reaction equation
Cl[C:2]1[S:6][N:5]([CH2:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:4](=[O:15])[CH:3]=1.[Na+].[CH2:17]([N:24]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[C:25](=[S:27])[S-:26])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[I-].[Na+]>C(O)C>[CH2:28]([N:24]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:25]([S:27][C:2]1[S:6][N:5]([CH2:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:4](=[O:15])[CH:3]=1)=[S:26])[C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1

Participants

5

Reactant 3

HCID 5238Sodium IodideHCID 4676203Carbamodithioic acid, bis(phenylmethyl)-, sodium saltHCID 13013787HCID 13013787, compound

Product 1

HCID 12852738HCID 12852738, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 4.8 g. (0.02 mole) of 5-chloro-2-phenethyl-4-isothiazolin-3-one in 35 ml of ethanol was added 5.9 g. (0.02 mole) of N,N-dibenzyldithiocarbamic acid sodium salt followed by 0.15 g. sodium iodide. The mixture was concentrated in vacuo and the residue was treated with 300 ml of boiling hexane under reflux. The hexane solution decanted and cooled to give 0.63 g. of the named product, mp 98°-100°.

Workup

  1. concentrationThe mixture was concentrated in vacuo
  2. additionthe residue was treated with 300 ml of boiling hexane
  3. temperatureunder reflux
  4. customThe hexane solution decanted
  5. temperaturecooled
  6. customto give 0.63 g

Sources & evidence

ORD record
ord-478a3cafc896449abcdd376d7e565764
Source dataset
uspto-grants-1982_01
Patent number
US04310590

Reaction notes

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