Hydrogen Peroxide → Methyl 3-methylanthranilate

Participants

Reaction Steps

15 parts of 50 percent strength by weight hydrogen peroxide solution are added slowly to a solution of 32.2 parts of 7-methylisatin and 12 parts of sodium methylate in 400 parts of methanol at 0° C. Thereafter, the mixture is stirred for 2 hours at room temperature and worked up as described in Example 1. 25.5 parts (78% of theory) of methyl 3-methylanthranilate, of melting point 27°-29° C., are obtained.

Provenance & Evidence