Hydrochloric Acid → HCID 23318282, compound

HRID 1105977Notes

Reaction equation

HRID 1105977 reaction equation
C([NH:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32])(=O)C.[ClH:33]>C(O)C>[ClH:33].[NH2:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20257269N-[5-tert-Butyl-4-(hexadecyloxy)-2-hydroxyphenyl]acetamide

Product 1

HCID 23318282HCID 23318282, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

23.0 g of 2-acetylamino-4-t-butyl-5-hexadecyloxyphenol obtained in Example 1, 120 ml of ethanol and 96 ml of 35% hydrochloric acid were blended, and the mixture was refluxed for 5 hours with stirring. After cooling the reaction solution, the crystals formed were separated by filtration to obtain 23.2 g of 2-amino-4-t-butyl-5-hexadecyloxyphenol hydrochloride.

Workup

  1. temperaturethe mixture was refluxed for 5 hours
  2. temperatureAfter cooling the reaction solution
  3. customthe crystals formed
  4. customwere separated by filtration

Sources & evidence

ORD record
ord-1418bddb349a44f3a4f31eaa2bf0ee4d
Source dataset
uspto-grants-1982_01
Patent number
US04310693

Reaction notes

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