(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → HCID 88745376, compound

HRID 1106018Notes

Reaction equation

HRID 1106018 reaction equation
[Na+:1].[CH2:2]([NH:18][C:19]1[CH:27]=[CH:26][C:22]([C:23]([O-:25])=[O:24])=[CH:21][CH:20]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[O:28]=[CH:29][C@@H:30]([C@H:32]([C@@H:34]([C@@H:36]([CH2:38][OH:39])[OH:37])[OH:35])[OH:33])[OH:31]>O>[O:28]=[CH:29][C@@H:30]([C@H:32]([C@@H:34]([C@@H:36]([CH2:38][OH:39])[OH:37])[OH:35])[OH:33])[OH:31].[Na+:1].[CH2:2]([NH:18][C:19]1[CH:20]=[CH:21][C:22]([C:23]([O-:25])=[O:24])=[CH:26][CH:27]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 23703815Cetaben Sodium

Product 1

HCID 88745376HCID 88745376, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A solution of 1.0 g. of p-hexadecylaminobenzoic acid sodium salt and 1.0 g. of dextrose in 12.5 ml. of water at 75-85° C. is frozen quickly by immersion in a -80° C. bath and lyophilized. The resulting solid coprecipitate is pulverized, providing an amorphous, water-soluble product.

Sources & evidence

ORD record
ord-3cb3cff3d1e34052b532dfdf86a2013d
Source dataset
uspto-grants-1982_01
Patent number
US04311694

Reaction notes

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