4-Hydroxybenzaldehyde → HCID 136087656, compound

HRID 1106105Notes

Reaction equation

HRID 1106105 reaction equation
[F:1][C:2]([F:14])([F:13])[CH2:3][N:4]1[C:8](=[O:9])[CH2:7][C:6]([C:10](=[O:12])[NH2:11])=[N:5]1.[OH:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1>COCCO>[F:14][C:2]([F:1])([F:13])[CH2:3][N:4]1[C:8](=[O:9])[C:7](=[CH:20][C:19]2[CH:22]=[CH:23][C:16]([OH:15])=[CH:17][CH:18]=2)[C:6]([C:10](=[O:12])[NH2:11])=[N:5]1

Participants

4

Reactant 2

HCID 1264-HydroxybenzaldehydeHCID 23463333HCID 23463333, compound

Product 1

HCID 136087656HCID 136087656, compound

Reagents, catalysts & solvents 1

HCID 80192-MethoxyethanolSolvent

Procedure

0.1 mole of 1-trifluoroethyl-3-carbamoyl-2-pyrazolin-5-one and 0.1 mole of p-hydroxybenzaldehyde were stirred for 1 hour in 150 ml of boiling ethylene glycol monomethyl ether. The solvent was distilled off under reduced pressure and the yellow dye was crystallized from methanol.

Workup

  1. distillationThe solvent was distilled off under reduced pressure
  2. customthe yellow dye was crystallized from methanol

Sources & evidence

ORD record
ord-7a2a6421d85c4a29920a8221e8d4e72d
Source dataset
uspto-grants-1982_01
Patent number
US04311787

Reaction notes

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