Dimethyl Sulfate → HCID 12909448, compound

Participants

Reaction Steps

The mixture of 3.0 g of 2-(p-chlorophenyl)-pyrazolo[4,3-c]quinolin-3(5H)-one and 100 ml of dimethyl sulfate is stirred at 110°-130° for 2 hours and evaporated. The residue is dissolved in N aqueous sodium hydroxide, the solution extracted with methylene chloride and the extract evaporated. The residue is recrystallized from diethyl ether, to yield the 1-methyl-2-(p-chlorophenyl)-pyrazolo[4,3-c]quinolin-3-one melting at 158°-161°.

Provenance & Evidence