HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → HCID 70514530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Reactant | (4-Fluorophenyl)hydrazine | HCID 69982 | — |
| Reactant | Ethyl 4-chloro-6-methoxyquinoline-3-carboxylate | HCID 304558 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 70514530 | HCID 70514530 | — |
Reaction Steps
The mixture of 2.7 g of ethyl 4-chloro-6-methoxyquinolin-3-carboxylate, 1.4 g of p-fluorophenylhydrazine and 20 ml of eutectic diphenyl ether-biphenyl is heated to 160°-165° for 4 hours, then cooled to room temperature and diluted with diethyl ether. The precipitated crystalline product is collected, washed thoroughly with diethyl ether and dried, to yield the 2-(p-fluorophenyl)-8-methoxypyrazolo]4,3-c]quinolin-3(5H)-one hydrochloride melting at 322°-324°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04312870 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-1df1237ac2e54981bba5b3d56c24ae21 |
| Source note | uspto-grants-1982_01 |