Hydrochloric Acid → HCID 21253084, compound

HRID 1106423Notes

Reaction equation

HRID 1106423 reaction equation
C([N:4]1[CH2:13][CH2:12][C:11]2[C:6](=[C:7]([NH:18]C(=O)C)[C:8]([N+:15]([O-:17])=[O:16])=[CH:9][C:10]=2[Br:14])[CH2:5]1)(=O)C.[ClH:22]>>[ClH:22].[Br:14][C:10]1[CH:9]=[C:8]([N+:15]([O-:17])=[O:16])[C:7]([NH2:18])=[C:6]2[C:11]=1[CH2:12][CH2:13][NH:4][CH2:5]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 21253072HCID 21253072, compound

Product 1

HCID 21253084HCID 21253084, compoundYield 77%

Procedure

A solution of the product from Example 4 (11.7 g, 32.8 mmol) and 3N HCl (400 mL) was heated to reflux for 4 hours. Upon cooling to room temperature, the solids were filtered, washed with 3N HCl and diethyl ether, and air dried to give the title compound (7.8 g, 77% yield) as a yellow solid, mp-305-307° C.

Workup

  1. temperatureto reflux for 4 hours
  2. filtrationthe solids were filtered
  3. washwashed with 3N HCl and diethyl ether, and air
  4. customdried

Sources & evidence

ORD record
ord-cdfbd31871e6432ba358e67e2df908c3
Source dataset
uspto-grants-2000_05
Patent number
US06057313

Reaction notes

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