Methanol → HCID 18788736, compound

HRID 1106498Notes

Reaction equation

HRID 1106498 reaction equation
[Br:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([CH3:14])[CH:3]=1.O=S(Cl)Cl.[CH3:19]O>>[Br:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6]([O:8][CH3:19])=[O:7])=[C:4]([CH3:14])[CH:3]=1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 187888904-Bromo-2-methyl-5-nitrobenzoic acid

Product 1

HCID 18788736HCID 18788736, compound

Procedure

14.3 g of 4-bromo-2-methyl-5-nitrobenzoic acid were dissolved in 250 ml of MeOH and 11.6 g of SOCl2 were slowly added dropwise. The mixture was allowed to stand at RT for 5 days, the volatile components were removed in vacuo and the residue is recrystallized from DIP.

Workup

  1. customthe volatile components were removed in vacuo
  2. customthe residue is recrystallized from DIP

Sources & evidence

ORD record
ord-389bcea3dda7445699161a224c184978
Source dataset
uspto-grants-2000_05
Patent number
US06057322

Reaction notes

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