Sodium Hydroxide → HCID 18788822, compound

Participants

Reaction Steps

2.6 g of methyl 2-methyl-4-phenyl-5-trifluoromethylbenzoate were dissolved in 100 ml of MeOH, 20 ml of a 1 N aqueous NaOH solution were added and the solution was stirred at RT for 8 h. The reaction mixture was poured onto 100 ml of a saturated aqueous NaHSO4 solution and extracted 3 times using 100 ml of EA each time. The organic phase was dried over Na2SO4 and the solvent was removed in vacuo.

Provenance & Evidence