HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21968284, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 9927305 | HCID 9927305 | — |
| Product | HCID 21968284 | HCID 21968284 | 90% |
Reaction Steps
A solution of (S)-4-[α-(hydroxymethyl)benzylamino]-6,7dimethoxyquinazoline (70 mg, 0.21 mmol) in acetic anhydride (2 ml) was stirred at room temperature for 3 h. Then water was added to the reaction mixture, the precipitate was filtered, washed with water and dried under vacuum. Thus pure title compound was obtained in 90% yield (71 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057326 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-12a96418812f419f8d557ebacdaa89cf |
| Source note | uspto-grants-2000_05 |