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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106513Generated: October 28, 2026

Water → HCID 21968284, compound

https://huagongshe.com/reaction/1106513

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantAcetic AnhydrideHCID 7918—
ReactantHCID 9927305HCID 9927305—
ProductHCID 21968284HCID 2196828490%

Reaction Steps

A solution of (S)-4-[α-(hydroxymethyl)benzylamino]-6,7dimethoxyquinazoline (70 mg, 0.21 mmol) in acetic anhydride (2 ml) was stirred at room temperature for 3 h. Then water was added to the reaction mixture, the precipitate was filtered, washed with water and dried under vacuum. Thus pure title compound was obtained in 90% yield (71 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057326
Source datasetuspto-grants-2000_05
ORD IDord-12a96418812f419f8d557ebacdaa89cf
Source noteuspto-grants-2000_05