2-Acetylbutyrolactone → HCID 178463338, Verbindung

HRID 1106521Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1106521
[NH2:1][C:2]1[CH:6]=[CH:5][NH:4][N:3]=1.[C:7]([CH:10]1[CH2:15][CH2:14][O:13][C:11]1=[O:12])(=O)[CH3:8]>C(O)C>[O:12]=[C:11]1[CH:10]([C:7](=[N:1][C:2]2[CH:6]=[CH:5][NH:4][N:3]=2)[CH3:8])[CH2:15][CH2:14][O:13]1

Komponenten

4

Edukt 2

HCID 106012-AcetylbutyrolactoneHCID 178418806HCID 178418806, Verbindung

Produkt 1

HCID 178463338HCID 178463338, VerbindungAusbeute 69,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

In 12 ml of anhydrous ethanol were added 0.83 g (10.00 mmol) of 3-aminopyrazole and 1.92 g (15.00 mmol) of 2-acetyl-γ-butyrolactone. While stirring at room temperature, 0.1 ml of a boron trifluoride methanol complex were added to the resultant solution, and the mixture was then stirred for 4 hours under the same conditions. Solids deposited were collected by filtration, washed with ethanol and air-dried to obtain 1.34 g (yield: 69.4%) of the intended product.

Aufarbeitung

  1. stirringthe mixture was then stirred for 4 hours under the same conditions
  2. filtrationSolids deposited were collected by filtration
  3. washwashed with ethanol
  4. customair-dried

Quellen und Nachweise

ORD-Eintrag
ord-ad8627edd42c4962a8e948051b019da6
Quelldatensatz
uspto-grants-2000_05
Patentnummer
US06057330

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