Cyclopentylamine → HCID 18789172, compound

HRID 1106532Notes

Reaction equation

HRID 1106532 reaction equation
Cl[CH2:2][CH2:3][C:4]1[C:5]([Cl:14])=[N:6][C:7]2[N:8]([N:11]=[CH:12][CH:13]=2)[C:9]=1Cl.[CH:15]1([NH2:20])[CH2:19][CH2:18][CH2:17][CH2:16]1>C(N(CC)CC)C>[Cl:14][C:5]1[C:4]2[CH2:3][CH2:2][N:20]([CH:15]3[CH2:19][CH2:18][CH2:17][CH2:16]3)[C:9]=2[N:8]2[N:11]=[CH:12][CH:13]=[C:7]2[N:6]=1

Participants

4

Reactant 2

HCID 2906CyclopentylamineHCID 18789177HCID 18789177, compound

Product 1

HCID 18789172HCID 18789172, compoundYield 187.6%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Synthesis was performed by the reaction of 11.0 g of 6-(2-chloroethyl)-5,7-dichloropyrazolo[1,5-a]pyrimidine with 1.80 g of cyclopentylamine and 8.87 g of triethylamine in accordance with the synthetic process in Example 54 to obtain 10.42 g (yield: 90.4%) of the intended product.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-6e872e6aeee847d28a99672d102d15f2
Source dataset
uspto-grants-2000_05
Patent number
US06057330

Reaction notes

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