Sec-Butylamine → HCID 18789132, compound

HRID 1106533Notes

Reaction equation

HRID 1106533 reaction equation
Cl[CH2:2][CH2:3][C:4]1[C:5]([Cl:14])=[N:6][C:7]2[N:8]([N:11]=[CH:12][CH:13]=2)[C:9]=1Cl.[CH:15]([NH2:19])([CH2:17][CH3:18])[CH3:16]>C(N(CC)CC)C>[CH:15]([N:19]1[C:9]2[N:8]3[N:11]=[CH:12][CH:13]=[C:7]3[N:6]=[C:5]([Cl:14])[C:4]=2[CH2:3][CH2:2]1)([CH2:17][CH3:18])[CH3:16]

Participants

4

Reactant 2

HCID 24874Sec-ButylamineHCID 18789177HCID 18789177, compound

Product 1

HCID 18789132HCID 18789132, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Synthesis was performed by the reaction of 5.26 g of 6-(2-chloroethyl)-5,7-dichloropyrazolo[1,5-a]pyrimidine with 4.00 g of sec-butylamine and 4.82 g of triethylamine in accordance with the synthetic process in Referential Example 9 to obtain 4.68 g (yield: 89.0%) of the intended product.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-06e4edb56f0a4189a291b0bed7f6e874
Source dataset
uspto-grants-2000_05
Patent number
US06057330

Reaction notes

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