HCID 15897849, compound → HCID 18789378, compound

HRID 1106667Notes

Reaction equation

HRID 1106667 reaction equation
[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]([CH3:46])[CH2:10][CH2:11][CH2:12][NH:13][C:14]([O:16][CH2:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:25]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45])=[O:26])=[O:15]>C(OCC)(=O)C>[ClH:1].[CH3:46][N:9]([CH3:8])[CH2:10][CH2:11][CH2:12][NH:13][C:14]([O:16][CH2:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:25]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45])=[O:26])=[O:15]

Participants

4

Reactant 2

HCID 15897849HCID 15897849, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 18789378HCID 18789378, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (1.28 ml) was added to a solution of octadecyl 2-{2-[N-[3-(dimethylamino)propyl]carbamoyloxy]ethyl}piperidinecarboxylate (1.55 g) in ethyl acetate (5 ml). After being stirred for 15 minutes at room temperature, the reaction mixture was concentrated, thereby yielding the entitled compound (1.38 g) as white wax.

Workup

  1. concentrationthe reaction mixture was concentrated

Sources & evidence

ORD record
ord-687922916f9141d3b8cce0372901b9aa
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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