Hydrogen chloride-ethyl acetate → HCID 86755376, compound

Participants

Reaction Steps

4N Hydrochloric acid/ethyl acetate solution (0.21 ml) was added to a solution of N-[3-(dimethylamino)propyl]-[2-(1-octadecyl-2-piperidyl)ethoxy]formamide (0.200 g) in ethyl acetate (4 ml) under argon gas atmosphere, while being cooled with ice. After being stirred for 15 minutes, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-hexane, thereby yielding the entitled compound (0.199 g) as white crystals.

Provenance & Evidence