HCID 9828101, compound → HCID 70131777, compound

HRID 1106673Notes

Reaction equation

HRID 1106673 reaction equation
[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]1[CH2:14][CH2:13][N:12]([C:15]([O:17][CH2:18][CH2:19][CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][N:21]2[C:26](=[O:44])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])=[O:16])[CH2:11][CH2:10]1>C(OCC)(=O)C>[ClH:1].[CH3:8][N:9]1[CH2:14][CH2:13][N:12]([C:15]([O:17][CH2:18][CH2:19][CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][N:21]2[C:26](=[O:44])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])=[O:16])[CH2:11][CH2:10]1

Participants

4

Reactant 2

HCID 9828101HCID 9828101, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 70131777HCID 70131777, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.11 ml) was added to a solution of 2-(1 -octadecanoyl-2-piperidyl)ethyl 4-methyltetrahydro- 1 (2H)-pyrazinecarboxylate (0.200 g) in ethyl acetate (2 ml). After being stirred for 15 minutes at room temperature, the reaction mixture was concentrated, thereby yielding the entitled compound (0.219 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated

Sources & evidence

ORD record
ord-5374c03ecc87492fbb75101caffeb935
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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