Potassium Carbonate → HCID 18789463, compound

HRID 1106678Notes

Reaction equation

HRID 1106678 reaction equation
[CH2:1]([N:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH:20]1[CH2:25][CH2:26][OH:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Br[CH2:29][CH2:30][CH2:31][CH2:32][Cl:33].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[Cl:33][CH2:32][CH2:31][CH2:30][CH2:29][O:27][CH2:26][CH2:25][CH:20]1[CH2:21][CH2:22][CH2:23][CH2:24][N:19]1[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 813641-Bromo-4-chlorobutaneHCID 18789398HCID 18789398, compound

Product 1

HCID 18789463HCID 18789463, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

2-(1-Octadecyl-2-piperidyl)ethan-1-ol and 1-bromo-4-chlorobutane are reacted in acetone in the presence of potassium carbonate at reflux temperature to obtain 2-[2-(4-chlorobutoxy)ethyl]-1-octadecylpiperidine.

Workup

  1. temperatureat reflux temperature

Sources & evidence

ORD record
ord-3e1e614b8f2c4bc6929c0cccb31dabcb
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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