4-Toluenesulfonyl chloride → HCID 18789426, compound

HRID 1106679Notes

Reaction equation

HRID 1106679 reaction equation
[CH2:1]([N:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH:20]1[CH2:25][CH2:26][OH:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[C:28]1([CH3:38])[CH:33]=[CH:32][C:31]([S:34](Cl)(=[O:36])=[O:35])=[CH:30][CH:29]=1.[OH-].[Na+]>O1CCOCC1>[CH2:1]([N:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH:20]1[CH2:25][CH2:26][O:27][S:34]([C:31]1[CH:32]=[CH:33][C:28]([CH3:38])=[CH:29][CH:30]=1)(=[O:36])=[O:35])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

5

Reactant 3

HCID 73974-Toluenesulfonyl chlorideHCID 14798Sodium HydroxideHCID 18789398HCID 18789398, compound

Product 1

HCID 18789426HCID 18789426, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1,4-Dioxane solution of 2-(1-octadecyl-2-piperidyl)ethan-1-ol and p-toluenesulfonyl chloride is added to sodium hydroxide solution and then the mixture is reacted at room temperature to obtain 1-octadecyl-2-[2-(tosyloxy)ethyl]piperidine.

Workup

  1. customthe mixture is reacted at room temperature

Sources & evidence

ORD record
ord-8021140bedfd42f28dc9032336d13f9f
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

Loading…