Potassium Carbonate → HCID 18789444, compound

HRID 1106681Notes

Reaction equation

HRID 1106681 reaction equation
[OH:1][CH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10](=[O:28])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27].Br[CH2:30][CH2:31][CH2:32][CH2:33][Cl:34].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[Cl:34][CH2:33][CH2:32][CH2:31][CH2:30][O:1][CH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10](=[O:28])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 813641-Bromo-4-chlorobutaneHCID 18789376HCID 18789376, compound

Product 1

HCID 18789444HCID 18789444, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

1-[2-(2-Hydroxyethyl)piperidino]octadecan-l-one and 1-bromo-4-chlorobutane are reacted in acetone in the presence of potassium carbonate at reflux temperature to obtain 2-[2-(4-chlorobutoxy)ethyl]-1-octadecanoylpiperidine.

Workup

  1. temperatureat reflux temperature

Sources & evidence

ORD record
ord-41792e8c37cb4c529f837c0caa6ad2b2
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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