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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106682Generated: October 31, 2026

2-Piperidin-2-ylethanol → HCID 86755378, compound

https://huagongshe.com/reaction/1106682

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Piperidin-2-ylethanolHCID 15144—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantHCID 22173960HCID 22173960—
SolventDimethylformamideHCID 6228—
ProductHCID 86755378HCID 86755378—

Reaction Steps

2-(2-Hydroxyethyl)piperidine, HOBt and WSCI are added to N,N-dimethylformamide solution of 4-chlorobutyrate while being cooled with ice and the mixture is reacted at room temperature to obtain 1-(4-(chlorobutanoyl)-2-(2-hydroxyethyl)piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057337
Source datasetuspto-grants-2000_05
ORD IDord-310f3313a8a242d199b178c88655ac08
Source noteuspto-grants-2000_05