Hydrochloric Acid → HCID 18789974, compound

Participants

Reaction Steps

A portion (1.6 g, 3.6 mmol) of the 1-(2-chloro-4-methanesulfonamidophenoxy]-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane produced in (4) above was dissolved in ethyl acetate (50 ml) and, thereafter, HCl was injected in a gaseous state (H2SO4 +NH4Cl) into the resulting solution as it was stirred at ordinary temperatures, thereby forming a precipitate. When no more precipitate was formed, the solvent was evaporated to yield the titled compound 1-(2-chloro-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride (1.7 g) as a pale yellow solid mass.

Provenance & Evidence