HCID 9910149, compound → HCID 9949483, compound

Participants

Reaction Steps

To a solution of N-(1-benzyl-4-piperidinyl)-2-butoxy-3-methyl-2-phenylbutanamide (invention compound, Compound No. 4) (4.5 g, 10.6 mmole) in ethanol (60 ml) was added palladium hydroxide-carbon (1.2 g), followed by hydrogenation for 6 hours at room temperature. The catalyst was filtered off and the filtrate was removed under reduced pressure to obtain the invention compound (Compound No. 27, quantitative yield) as a colorless oil.

Provenance & Evidence