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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1107432Generated: October 30, 2026

Dimethylformamide → α-Phenyl-4-pyridineacetonitrile

https://huagongshe.com/reaction/1107432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPhenylacetonitrileHCID 8794—
ReactantPotassium tert-butoxideHCID 23665647—
Productα-Phenyl-4-pyridineacetonitrileHCID 12870734—

Reaction Steps

The compound was prepared substantially in accordance with the procedure detailed in Example 12A, using the compound of Example 15A, benzyl cyanide (3.3 ml, 28.7 mmol) and potassium t-butoxide (6.44 g, 57.4 mmol) in 60 ml of DMF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06060484
Source datasetuspto-grants-2000_05
ORD IDord-f03a0112de8e440ebef88f3fd2099a80
Source noteuspto-grants-2000_05