HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Oxo-1-phenylcyclohexanenitrile → 4-Hydroxy-1-phenylcyclohexane-1-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Oxo-1-phenylcyclohexanenitrile | HCID 91282 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Hydroxy-1-phenylcyclohexane-1-carbonitrile | HCID 12453673 | — |
Reaction Steps
A cold (0° C.) solution of 4-cyano-4-phenylcyclohexanone (5.0 g, 25.1 mmol) in 30 ml of MeOH was treated with sodium borohydride (1.14 g, 30.1 mmol). The reaction mixture was stirred for 2 hours at room temperature and then concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060484 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-cc8638597dbb48998b118474e48653ff |
| Source note | uspto-grants-2000_05 |