HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzoic Acid → 1-Phenyl-2-(phenylsulphonyl)ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzoic Acid | HCID 6318 | — |
| Reactant | 2-Naphthoic acid | HCID 7123 | — |
| Reactant | 1,3-Benzodioxole-5-carboxylic acid | HCID 7196 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 3,4,5-Trimethoxybenzoic Acid | HCID 8357 | — |
| Reactant | 3-(Trifluoromethyl)benzoic acid | HCID 9963 | — |
| Reactant | 2-Phenylpropionic acid | HCID 10296 | — |
| Reactant | 3-Methoxybenzoic Acid | HCID 11461 | — |
| Reactant | 3-(Dimethylamino)benzoic acid | HCID 66837 | — |
| Reactant | p-(Methylsulphonyl)benzoic acid | HCID 77670 | — |
| Reactant | 3,5-Difluorobenzoic acid | HCID 101265 | — |
| Reactant | 6-Methoxy-2-Naphthoic Acid | HCID 349181 | — |
| Reactant | 4-Methanesulfinylbenzoic acid | HCID 4961892 | — |
| Reactant | 2-(1,3-Dioxaindan-5-yl)propanoic acid | HCID 18399654 | — |
| Reactant | HCID 21188426 | HCID 21188426 | — |
| Product | 1-Phenyl-2-(phenylsulphonyl)ethan-1-one | HCID 76949 | — |
Reaction Steps
When the acid chloride of 4-chlorobenzoic acid, 3-methoxybenzoic acid, 3,4-methylenedioxybenzoic acid, 3,4,5-trimethoxybenzoic acid, 3-trifluoromethylbenzoic acid, 3-dimethylaminobenzoic acid, 4-methylthiobenzoic, 4-methylsulfinylbenzoic acid, 4methylsulfonylbenzoic acid, 3,5-difluorobenzoic acid, 2-naphthoic acid, 4-dimethylamino-2-naphthoic acid, 6-methoxy-2-naphthoic acid, 2-phenylpropionic acid and 2-(3,4-methylenedioxyphenyl) propionic acid are used in place of benzoyl chloride above, the corresponding substituted ketosulfones are prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060473 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-1680a0eb66e74967bfeb508ad0125602 |
| Source note | uspto-grants-2000_05 |