HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,3-Dimethyl-7-(1-diethylamino-2-hydroxyethyl)benzofuran hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2,3-Dimethyl-7-(1-diethylamino-2-hydroxyethyl)benzofuran | HCID 15407956 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2,3-Dimethyl-7-(1-diethylamino-2-hydroxyethyl)benzofuran hydrochloride | HCID 18787518 | — |
Reaction Steps
0.55 mg of 2,3-dimethyl-7-(1-diethylamino-2-hydroxyethyl)benzofuran and 100 ml of a 0.1N solution of hydrochloric acid in isopropanol are placed in a 100 ml round-bottom flask. The salt is concentrated under vacuum and recrystallized from ethyl acetate. 0.561 g of 2,3-dimethyl-7-(1-diethylamino-2-hydroxyethyl)benzofuran hydrochloride is obtained. M.p.=160-161° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060508 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-c1ce0b11e9274ec8b3c23b4b127a8f3a |
| Source note | uspto-grants-2000_05 |