HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,3-Dimethyl-7-[1,2-di(diethylamino)ethyl]benzofuran hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2,3-Dimethyl-7-[1,2-di(diethylamino)ethyl]benzofuran | HCID 18787512 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2,3-Dimethyl-7-[1,2-di(diethylamino)ethyl]benzofuran hydrochloride | HCID 18787517 | 88% |
Reaction Steps
400 mg of 2,3-dimethyl-7-[1,2-di(diethylamino)ethyl]benzofuran and 10 ml of a solution of hydrochloric acid in isopropanol are placed in a 100 ml round-bottomed flask. The salt is concentrated under vacuum and recrystallized from ethyl acetate. 400 mg (Yield: 88%) of 2,3-dimethyl-7-[1,2-di(diethylamino)ethyl]benzofuran hydrochloride are obtained. M.p.=183° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060508 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-3f31e1e48eff4a38b4f31232b7f4100e |
| Source note | uspto-grants-2000_05 |