反应详情

Cyclohexene oxide (982 mg, 10 mmol), pyrolidine (2.134 g, 30 mmol), and 1.8 mL of water were heated at 90° C. for 18 hours. The reaction was then cooled and diluted with 75 mL of diethyl ether. The mixture was then washed with aqueous sodium bicarbonate (15 mL), brine (2×15 mL), dried over magnesium sulfate, filtered, and evaporated to give 1.499 g (89%) of the title compound.

1. temperatureThe reaction was then cooled
2. washThe mixture was then washed with aqueous sodium bicarbonate (15 mL), brine (2×15 mL)
3. dry with materialdried over magnesium sulfate
4. filtrationfiltered
5. customevaporated