Nitric Acid → HCID 178518238, compound

Participants

Reaction Steps

Primidone, 1.60 g, was dissolved with stirring in 8 ml concentrated sulfuric acid and cooled in ice. A cold solution of 485 μl concentrated nitric acid in 2 ml concentrated sulfuric acid was added over a period of 10 minutes. After 2 hours at 0° C. the reaction mixture was poured into ice water neutralized with cold sodium hydroxide. The precipitate was collected, washed with water and dried in vacuo affording 1.79 g white solid.

Provenance & Evidence