HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chloro-2-fluorophenyl)methanol → 1-(2-Butenyl)-7-(4-chloro-2-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chloro-2-fluorophenyl)methanol | HCID 2773609 | — |
| Reactant | 1-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53719624 | — |
| Product | 1-(2-Butenyl)-7-(4-chloro-2-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 54169100 | 63.8% |
Reaction Steps
The title compound (cis/trans=24:76) was prepared as a white powder in 63.8% yield in a similar procedure to that described in Example 1 by using using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=24/76) and 4-chloro-2-fluorobenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063782 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-6e79ae1002d244bcb6e57d10784ff960 |
| Source note | uspto-grants-2000_05 |