HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,4-Difluorophenyl)methanethiol → 1-(2-Butenyl)-7-(2,4-difluorobenzylthio)-2,3-dimethylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,4-Difluorophenyl)methanethiol | HCID 2761425 | — |
| Reactant | 1-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53719624 | — |
| Product | 1-(2-Butenyl)-7-(2,4-difluorobenzylthio)-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 54268533 | 39% |
Reaction Steps
The title compound (cis/trans=16:84) was prepared as pale brown crystals in 39.0% yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=22/78) and 2,4-difluorophenylmethanethiol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063782 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-fb58787a2d424ef18e857549fd475069 |
| Source note | uspto-grants-2000_05 |