HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorobenzyl alcohol → 7-(2,4-Difluorobenzyloxy)-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorobenzyl alcohol | HCID 91867 | — |
| Reactant | 7-Chloro-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazine | HCID 22719650 | — |
| Product | 7-(2,4-Difluorobenzyloxy)-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazine | HCID 18756069 | 63.8% |
Reaction Steps
The title compound (trans) was prepared as a white powder in 63.8% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazine and 2,4-difluorobenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063782 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-6eeb191e73294f8fad23f4afd52c0d70 |
| Source note | uspto-grants-2000_05 |