Bromomethylcyclopropane → HCID 18785651, compound

HRID 1107826Notes

Reaction equation

HRID 1107826 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]=1[CH3:7].Br[CH2:19][CH:20]1[CH2:22][CH2:21]1>>[CH:20]1([CH2:19][N:3]2[C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:5][C:6]([CH3:7])=[C:2]2[CH3:1])[CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 81503BromomethylcyclopropaneHCID 18785604HCID 18785604, compound

Product 1

HCID 18785651HCID 18785651, compoundYield 93%

Procedure

The title compound was prepared as an orange oil in 93.0% yield in a similar procedure to that described in Referential Example 97 by using 2,3-dimethyl-5-(3-phenylpropionyl)pyrrole and bromomethylcyclopropane.

Sources & evidence

ORD record
ord-e7e62831dd3b4b7b95d67c77f6123f3c
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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