Water → HCID 54356745, compound

HRID 1107832Notes

Reaction equation

HRID 1107832 reaction equation
[S:1]([CH:13]1[CH2:19][CH2:18][CH2:17][CH2:16][CH:15]([NH2:20])[CH2:14]1)[C@@H:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4].[C:21](OC(=O)C)(=[O:23])[CH3:22].O>CO>[S:1]([CH:13]1[CH2:19][CH2:18][CH2:17][CH2:16][CH:15]([NH:20][C:21](=[O:23])[CH3:22])[CH2:14]1)[C@@H:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4]

Participants

5

Reactant 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 54519923HCID 54519923, compound2×

Product 1

HCID 54356745HCID 54356745, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In one example, the primary amine group of compound B5 can optionally be acylated by contacting B5 with an excess of acetic anhydride in methanol containing a trace of water. Generally, this reaction is conducted at about 25° C. to about 30° C. for about 2 to about 24 hours to provide for 3-acetamidocycloheptyl 1-thio-β-galactopyranoside, C5.

Workup

  1. waitGenerally, this reaction is conducted at about 25° C. to about 30° C. for about 2 to about 24 hours

Sources & evidence

ORD record
ord-aaeed0e6bfb94e21b5c3385b5ce6f9ff
Source dataset
uspto-grants-2000_05
Patent number
US06063769

Reaction notes

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