2-Methoxyaniline → HCID 18782298, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 28.4 g (0.23 mol) of 2-methoxyaniline and 43.2 g (0.28 mol) of 1,1,1-trifluoro-2,4-pentanedione is prepared and heated at 100-105° C. for 1 h, with stirring. After cooling, the reaction mixture is redissolved in ethyl ether and the solution obtained is dried over sodium sulfate and then concentrated under reduced pressure to give 59.1 g of the expected product in the form of a beige solid (yield=99%).

Provenance & Evidence