HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-(2-Benzyloxyethyl)thio-2',4'-difluoroacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-1-(2,4-difluorophenyl)ethanone | HCID 588083 | — |
| Reactant | Ethanethiol, 2-(phenylmethoxy)- | HCID 14571805 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(2-Benzyloxyethyl)thio-2',4'-difluoroacetophenone | HCID 18786643 | 80.8% |
Reaction Steps
Using 2-chloro-2',4'-difluoroacetophenone (4.5 g, 0.024 mol), 2-benzyloxyethanethiol (4.2 g, 0.025 mol), potassium carbonate (4.0 g, 0.029 mol) and methanol (50 ml), 2-(2-benzyloxyethyl)thio-2',4'-difluoroacetophenone (6.2 g, yield: 80.8%) was obtained as a colorless oil by similar procedures to Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063945 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-0580ba2608454e1892fce587626d7b2d |
| Source note | uspto-grants-2000_05 |